Cell Line

ML IV-2

Cell Type

Human iPSCs from Saudi patient

Disease

Mucolipidosis

Mutation

Homozygous mutation in MCOLN1 gene c.785T>C p.(F262S)

Sex

Female

Age at Collection

5 Years

Reprogramming Method

Peripheral blood mononuclear cells (PBMCs)

Number of Generated Clones

Not available

Stock Availability

Not available

Recommended Culture Type and Media

Adherent. mTeSR plus

Cell Morphology

Tightly packed colonies with smooth edges, small round cells, large nuclei with a high nucleus-to-cytoplasm ratio, and minimal cytoplasm, reflecting their pluripotency

Common Applications

-      Disease Modeling

-      Drug Discovery and Development

-      Regenerative Medicine

-      Tissue Engineering

-      Toxicology Testing

-      Gene Therapy Research

-      Personalized Medicine

-      Developmental Biology Studies

-      Bioprinting

-      Cell Therapy