Cell Line

LQT

Cell Type

Human iPSCs from Saudi patient

Disease

Long QT syndrome

Mutation

Heterozygous mutation in KCNH2 gene c.2344dup p.(Ile782Asnfs*22)

Sex

Female

Age at Collection

30

Reprogramming Method

Erythroid progenitor cells (EPCs) (CD71/CD235 positive cells)

Number of Generated Clones

2

Stock Availability

50

Recommended Culture Type and Media

Adherent. mTeSR plus

Cell Morphology

Tightly packed colonies with smooth edges, small round cells, large nuclei with a high nucleus-to-cytoplasm ratio, and minimal cytoplasm, reflecting their pluripotency

Common Applications

-      Disease Modeling

-      Drug Discovery and Development

-      Regenerative Medicine

-      Tissue Engineering

-      Toxicology Testing

-      Gene Therapy Research

-      Personalized Medicine

-      Developmental Biology Studies

-      Bioprinting

-      Cell Therapy