Cell Line

FOP

Cell Type

Human iPSCs from Saudi patient

Disease

Fibrodysplasia ossificans progressiva

Mutation

Heterozygous Pathogenic variant mutation in ACVR1 gene

Sex

Female

Age at Collection

22

Reprogramming Method

Peripheral blood mononuclear cells (PBMCs)

Number of Generated Clones

2

Stock Availability

35

Recommended Culture Type and Media

Adherent. mTeSR plus

Cell Morphology

Tightly packed colonies with smooth edges, small round cells, large nuclei with a high nucleus-to-cytoplasm ratio, and minimal cytoplasm, reflecting their pluripotency

Common Applications

-      Disease Modeling

-      Drug Discovery and Development

-      Regenerative Medicine

-      Tissue Engineering

-      Toxicology Testing

-      Gene Therapy Research

-      Personalized Medicine

-      Developmental Biology Studies

-      Bioprinting

-      Cell Therapy